In Vivo Cell Tracking with Bioluminescence Imaging
نویسندگان
چکیده
منابع مشابه
In vivo bioluminescence for tracking cell fate and function.
Tracking the fate and function of cells in vivo is paramount for the development of rational therapies for cardiac injury. Bioluminescence imaging (BLI) provides a means for monitoring physiological processes in real time, ranging from cell survival to gene expression to complex molecular processes. In mice and rats, BLI provides unmatched sensitivity because of the absence of endogenous lucife...
متن کاملDynamic tracking of human hematopoietic stem cell engraftment using in vivo bioluminescence imaging.
The standard approach to assess hematopoietic stem cell (HSC) engraftment in experimental bone marrow transplantation models relies on detection of donor hematopoietic cells in host bone marrow following death; this approach provides data from only a single time point after transplantation for each animal. In vivo bioluminescence imaging was therefore explored as a method to gain a dynamic, lon...
متن کاملBioluminescence imaging of lymphocyte trafficking in vivo.
Lymphocytes are highly mobile cells that travel throughout the body in response to a tremendous variety of stimuli. Revealing lymphocyte trafficking patterns in vivo is necessary for a complete understanding of immune function, as well as cell-cell and cell-tissue interactions in immune development and in response to insult. Although the location of cell populations in various tissues at any gi...
متن کاملIn vivo cell tracking by bioluminescence imaging after transplantation of bioengineered cell sheets to the knee joint.
In our previous studies, we have demonstrated effective regeneration of cartilage through the creation and application of layered cell sheets that combine both chondrocytes and synovial cells. In this study, we were able to demonstrate that cells derived from cell sheets can survive for long periods after transplantation into rat knee joints having osteochondral defects. We established a method...
متن کاملIn vivo tracking of human neural progenitor cells in the rat brain using bioluminescence imaging
BACKGROUND Stem cell therapies appear promising for treating certain neurodegenerative disorders and molecular imaging methods that track these cells in vivo could answer some key questions regarding their survival and migration. Bioluminescence imaging (BLI), which relies on luciferase expression in these cells, has been used for this purpose due to its high sensitivity. NEW METHOD In this s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nuclear Medicine and Molecular Imaging
سال: 2014
ISSN: 1869-3474,1869-3482
DOI: 10.1007/s13139-014-0309-x